Comparative Magnitude of Cross-Strain Conservation of HIV Variable Loop Neutralization Epitopes
نویسندگان
چکیده
منابع مشابه
Comparative Magnitude of Cross-Strain Conservation of HIV Variable Loop Neutralization Epitopes
Although the sequence variable loops of the human immunodeficiency virus' (HIV-1) surface envelope glycoprotein (gp120) can exhibit good immunogenicity, characterizing conserved (invariant) cross-strain neutralization epitopes within these loops has proven difficult. We recently developed a method to derive sensitive and specific signature motifs for the three-dimensional (3D) shapes of the HIV...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0015994